My belief, developed during the study of this science, is that destiny depends on four major things in equal proportion.
As we all are aware, there are planets which by their interaction, govern our destiny. Also there are groups of people who talk about the benefits of yoga, mantra, yantra and allied topics, each of which has a scientific logic as is the case with the manuscripts left behind by the Rishis. There are large number of books available in the public domain which talks about various remedial methods that could be followed.